� For the first time researchers have proved that there is a genetic susceptibleness to developing chronic lymphocytic leukaemia (CLL), the most common contour of cancer of the blood in the Western earthly concern.
Whilst anecdotal evidence has suggested that inherited factors play a role in the ontogenesis of CLL, scientists suffer until now been unable to prove a transmissible basis.
A study chiefly funded by Leukaemia Research with additional funding from Cancer Research UK and carried verboten at The Institute of Cancer Research has proved that variation in sure genes do play a part and this testament open the way for better treatment of existing patients. It may likewise lead to preventive practice of medicine for the disease in the future.
The results of the research are published in the journal Nature Genetics (31 August).
Close relatives, i.e. siblings, parents or children, of patients with chronic lymphocytic cancer of the blood have a seven-times higher chance of developing this blood crab compared with the general population. For many cancers such as breast cancer, part of the familial risk is caused by a single major disease-risk gene - but no such factor exists for CLL.
The new research has confirmed that the inheritance of a number of low-risk genes john explain role of the inherited susceptibility to develop CLL. Professor Richard Houlston and his team at The Institute of Cancer Research compared DNA from CLL patients with DNA from a healthy grouping. They have found hexad genes with variations in their hereditary sequences that are strongly associated with the development of CLL.
Professor Houlston explains the findings: " This research provides strong evidence that CLL, in at least some cases, is caused by a combination of different genetic variations which ar inherited. Each of these variations, by itself, has a very small event on the risk of developing CLL, but when all of them are present there is a significantly increased risk of leukaemia. Now that we have this evidence we can run out studies to make up one's mind exactly how the different genes contribute to this risk. "
Dr David Grant, Scientific Consultant at Leukaemia Research, says: " This finding is selfsame exciting as it carries the hypothesis of up treatments for individuals world Health Organization we cognize are at risk of developing this leukaemia. Clinical applications ar still a little patch away but this is a very important step forward in understanding the basis of this common leukaemia. "
1. The account is promulgated online from 31 August 2008 in the diary Nature Genetics under the title "A genome-wide association study identifies six susceptibility loci for chronic lymphocytic leukemia". Corresponding author: Dr Richard Houlston, Institute of Cancer Research, Sutton, Surrey.
2. Leukaemia Research provided principal financing for the study. Additional funding was provided by CLL Global Research Foundation, Cancer Research UK, the Arbib fund, and the European Union. Author Dalemari Crowther-Swanepoel (DC-S) was in receipt of a PhD studentship from The Institute of Cancer Research.
3. Chronic lymphocytic leukaemia is a lento progressing var. of leucaemia, characterised by an increased number of white blood cells known as lymphocytes. With about 2,750 new cases occurring each year in the UK, it is the most common chassis of leukaemia and occurs predominantly in late middle age forwards. It has variable symptoms and course, but crataegus oxycantha be diagnosed by probability before the patient develops any clinical symptoms of the disease.
The Institute of Cancer Research
The Institute of Cancer Research is Europe ' s starring cancer inquiry centre with expert scientists working on cutting sharpness research. It was founded in 1909 to carry out research into the causes of cancer and to develop new strategies for its prevention, diagnosing, treatment and care. For more information visit hTTP://www.icr.ac.uk.
The Institute is a charity that relies on voluntary income. The Institute is one of the world ' s nearly cost-effective major cancer research organisations with over 950p in every � of total income directly supporting research.
Leukaemia Research
Leukaemia Research is the only national charity devoted exclusively to improving treatments, finding cures and learning how to prevent leukaemia, Hodgkin's and other lymphomas, myeloma and the related blood disorders, diagnosed in 24,five hundred people in the UK every year.
Cancer Research UK
- Together with its partners and supporters, Cancer Research UK's vision is to pulsate cancer.
- Cancer Research UK carries out foremost research to improve understanding of the disease and find out how to prevent, diagnose and treat different kinds of cancer.
- Cancer Research UK ensures that its findings are secondhand to meliorate the lives of all cancer patients.
- Cancer Research UK helps people to realize cancer, the progress that is existence made and the choices each person can make.
- Cancer Research UK works in partnership with others to achieve the greatest encroachment in the global fight against crab.
Cancer Research UK
More information
Tuesday, 2 September 2008
Saturday, 23 August 2008
DJ Alex Zane Suspended For Airing 'Joke Rape Song'
DJ Alex Zane has been suspended from his role as host of the Xfm Breakfast show after acting a vocal about rape on air.
The DJ played the �tongue in cheek� track, entitled �Code Of Love�, on Wednesday morning.
Listeners described the song as �nothing bad� but in a
Wednesday, 13 August 2008
Brad Paisley pushes 'Play' on Election Day album release
Currently in the middle of a lengthy summer tour, Brad Paisley [ ] has announced an Election Day (Nov. 4) release
Wednesday, 6 August 2008
Detroit News Examines Debate Over Certified Professional Midwives' Qualifications
�The Detroit News on Tuesday examined the fence between the medical community and base birth advocates over where women should give birthing and wHO is best qualified to perform deliveries. According to CDC's National Center for Health Statistics, about 1% of births annually ar performed outside of hospitals.
The American Medical Association last month issued a statement that aforementioned the "safest setting for labor, delivery and the immediate postpartum period is in the hospital, or a parturition center within a hospital complex." AMA and the American College of Obstetricians and Gynecologists also hold said a hospital is the safest place to give nascency because medical staff ar readily available if complications arise. The groups too have said that physicians and certified nurse midwives, who have got formal nursing certification, ar the almost appropriate professionals to oversee deliveries. Certified nurse-midwives ar licensed in all states and to the highest degree often recitation in hospitals or medical centers.
However, many home birth advocates take said that formal breast feeding certification is not necessary for a midwife to oversee home births and that certified professional midwives, who do not have nursing enfranchisement, are able-bodied to supervise births successfully. About half of states license CPMs, although many midwife advocates are calling for linguistic universal licensure of CPMs to expand birth options for women. Many medical groups have aforesaid CPMs, wHO must pitch 40 infants to be certified, do not receive enough training to palm complications.
Steffany Hedenkamp, communication theory coordinator for The Big Push for Midwives Campaign, said medical groups' efforts to limit CPMs ar "anti-competitive," adding, "With this integration of [CPMs] we see increased access to care." Erin Tracy, an ob-gyn at Massachusetts General Hospital, said the 40 deliveries CPMs are mandatory to oversee is "less than ... interns do in one calendar month," adding, "You need more of a medical setting to empathise medical complications" (Detroit News, 7/29).
Reprinted with kind permission from hypertext transfer protocol://www.nationalpartnership.org. You can scene the entire Daily Women's Health Policy Report, search the archives, or sign up for email delivery here. The Daily Women's Health Policy Report is a liberate service of the National Partnership for Women & Families, promulgated by The Advisory Board Company.
More info
The American Medical Association last month issued a statement that aforementioned the "safest setting for labor, delivery and the immediate postpartum period is in the hospital, or a parturition center within a hospital complex." AMA and the American College of Obstetricians and Gynecologists also hold said a hospital is the safest place to give nascency because medical staff ar readily available if complications arise. The groups too have said that physicians and certified nurse midwives, who have got formal nursing certification, ar the almost appropriate professionals to oversee deliveries. Certified nurse-midwives ar licensed in all states and to the highest degree often recitation in hospitals or medical centers.
However, many home birth advocates take said that formal breast feeding certification is not necessary for a midwife to oversee home births and that certified professional midwives, who do not have nursing enfranchisement, are able-bodied to supervise births successfully. About half of states license CPMs, although many midwife advocates are calling for linguistic universal licensure of CPMs to expand birth options for women. Many medical groups have aforesaid CPMs, wHO must pitch 40 infants to be certified, do not receive enough training to palm complications.
Steffany Hedenkamp, communication theory coordinator for The Big Push for Midwives Campaign, said medical groups' efforts to limit CPMs ar "anti-competitive," adding, "With this integration of [CPMs] we see increased access to care." Erin Tracy, an ob-gyn at Massachusetts General Hospital, said the 40 deliveries CPMs are mandatory to oversee is "less than ... interns do in one calendar month," adding, "You need more of a medical setting to empathise medical complications" (Detroit News, 7/29).
Reprinted with kind permission from hypertext transfer protocol://www.nationalpartnership.org. You can scene the entire Daily Women's Health Policy Report, search the archives, or sign up for email delivery here. The Daily Women's Health Policy Report is a liberate service of the National Partnership for Women & Families, promulgated by The Advisory Board Company.
More info
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Thursday, 26 June 2008
Unida
Artist: Unida
Genre(s):
Other
Discography:
Coping With The Urban Coyote
Year: 1999
Tracks: 8
Following the dissolution of lapidator sway icons Kyuss, vocalist John Garcia formed Unida with guitar player Arthur Seay, bassist Dave Dinsmore, and drummer Mike Cancino. Debuting in late 1998 with the EP The Best of Wayne-Gro, Unida resurfaced in mid-1999 with the full-length Cope With the Urban Coyote; undermentioned Dinsmore's going, he was replaced by bassist Scott Reeder.
Wednesday, 18 June 2008
Stamatis Spanoudakis
Artist: Stamatis Spanoudakis
Genre(s):
New Age
Discography:
Nifes
Year: 2004
Tracks: 14
Brides
Year: 2004
Tracks: 14
Stamatis Spanoudakis - Kommati Apo Tin Psihi Mou (2003)
Year: 2003
Tracks: 14
Kommati Apo Tin Psihi Mou
Year: 2003
Tracks: 14
Kai To Xeres Cd1
Year: 2002
Tracks: 12
Gia Tin Smyrni
Year: 2001
Tracks: 14
Marble King Marmaromenos Vasilhas
Year: 1998
Tracks: 14
To Dakry Tou Ioanni
Year: 1996
Tracks: 12
W Glyky Mou Ear
Year: 1990
Tracks: 6
The Holy Hour Earini Ora
Year:
Tracks: 10
Thalassa
Year:
Tracks: 10
Moments Gone 3 Horis Logia 3
Year:
Tracks: 13
Moments Gone 2 Horis Logia 2 Eimai Zontanos Epidi Se Agapisa
Year:
Tracks: 12
Moments Gone 1 Horis Logia 1 I Stigmi Pou Pernaei Kai Hanetai
Year:
Tracks: 12
Alexandros
Year:
Tracks: 14
 
Monday, 9 June 2008
Alphawezen
Artist: Alphawezen
Genre(s):
Dance
Electronic
Other
Discography:
Comme Vous Voulez
Year: 2007
Tracks: 14
Welcome to Machinarchy
Year: 2004
Tracks: 3
En Passant
Year: 2004
Tracks: 12
L'apres Midi D'un Microphone
Year: 2001
Tracks: 12
Into The Stars
Year: 2001
Tracks: 4
 
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